Attribution of Congenital Cytomegalovirus Infection to Primary Versus Non-Primary Maternal Infection
نویسندگان
چکیده
منابع مشابه
Symptomatic congenital cytomegalovirus disease following non-primary maternal infection: a retrospective cohort study
BACKGROUND Scarce data exist about screening, diagnosis and prognosis of non-primary Cytomegalovirus (CMV) during pregnancy. We aimed to examine antenatal diagnosis of maternal non-primary CMV infection and to identify risk factors for congenial CMV disease. METHODS Retrospective cohort of 107 neonates with congenital symptomatic CMV infection, following either primary (n = 95) or non-primary...
متن کاملDiagnosis of Maternal and Congenital Cytomegalovirus Infection
Human cytomegalovirus (CMV) is one of the eight viruses belonging to the Herpesviridae family to infect humans. CMV belongs to the Betaherpesvirinae subfamily of viruses characterized by a restricted host spectrum, in vitro replication in fibroblasts of the natural host species in vivo, a slow replication cycle, the induction of intranuclear and intracytoplasmic inclusions and the ability to in...
متن کاملCongenital cytomegalovirus infection: predisposing maternal factors.
In a prospective study of cytomegalovirus (CMV) infection in pregnancy 69 congenitally infected infants were identified. The age, race, marital status, social class, and parity of the mothers of congenital CMV infants were compared with those of the screened population of women with non-infected infants. These factors were all individually strongly associated with the prevalence of congenital C...
متن کاملPrimary versus Nonprimary Cytomegalovirus Infection during Pregnancy, Israel
We examined prospectively the outcome of primary and nonprimary maternal cytomegalovirus (CMV) infection during pregnancy among 88 and 120 women, respectively. The risk for vertical transmission was 1.83x higher for primary infection than for nonprimary infection. Nonetheless, congenital CMV disease was diagnosed in both infection groups at similar rates.
متن کاملFetal effects of primary and non-primary cytomegalovirus infection in pregnancy: are we close to prevention?
Seroconversion to cytomegalovirus occurs in 1-4% of pregnant women, most of whom are seropositive prior to pregnancy. In 0.2-2.5% of their newborn infants there is evidence of intrauterine infection; most are born without any clinical findings The typical clinical symptoms of symptomatic congenital CMV are observed in 10-20% of infected neonates. They include intrauterine growth restriction, mi...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2010
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/ciq085